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Study shows drug developers circumspect about using social media in clinical research

Date: Mar-10-2014
Social media is gaining ground as an important tool to improve the clinical research process through more effective engagement of patient communities, but drug sponsors are proceeding cautiously, according to an analysis recently completed by the Tufts Center for the Study of Drug Development.

Shedding new light on marijuana's anxiety relief effects

Date: Mar-10-2014
An international group led by Vanderbilt University researchers has found cannabinoid receptors, through which marijuana exerts its effects, in a key emotional hub in the brain involved in regulating anxiety and the flight-or-fight response.This is the first time cannabinoid receptors have been identified in the central nucleus of the amygdala in a mouse model, they report in the current issue of the journal Neuron.The discovery may help explain why marijuana users say they take the drug mainly to reduce anxiety, said Sachin Patel, M.D., Ph.D.

Unravelling the hidden variation of bacteria fighting for survival in the gut

Date: Mar-10-2014
Our intestines harbour an astronomical number of bacteria, around 100 times the number of cells in our body, known as the gut microbiota. These bacteria belong to thousands of species that co-exist, interact with each other and are key to our health. While it is clear that species imbalances may result in disease, it is unclear at what pace does each species in the gut evolves, a process that contributes to the chance of a particular innocuous species becoming harmful to the host.

Childhood physical abuse a concern in attention deficit disorder

Date: Mar-10-2014
Thirty percent of adults with Attention Deficit Disorder or Attention Deficit Hyperactivity Disorder (ADD/ADHD) report they were physically abused before they turned 18. This compares to seven per cent of those without ADD/ADHD who were physically abused before 18. The results were in a study published in this week's online Journal of Aggression, Maltreatment, and Trauma.

Enzyme controls transport of genomic building blocks

Date: Mar-10-2014
Our DNA and its architecture are duplicated every time our cells divide. Histone proteins are key building blocks of this architecture and contain crucial information that regulates our genes. Danish researchers show how an enzyme controls reliable and high-speed delivery of histones to DNA copying hubs in our cells. This shuttling mechanism is crucial to maintain normal function of our genes and prevent disease. The results are published in the journal Nature Communications.

Keeping veterans out of criminal justice system by increasing access to social workers

Date: Mar-10-2014
Approximately one in six veterans struggles with substance abuse, and 20 percent show signs of mental health issues or cognitive impairments, previous research has shown. These risk factors, combined with a lack of resources, could be contributing to an increase of veterans entering the criminal justice system, according to a report by the Center for Mental Health Services. Now, University of Missouri researchers have investigated ways social workers can address veterans' needs and keep them out of jail.

Identification of gene important to breast development and breast cancer

Date: Mar-10-2014
Understanding more about how the different types of cells in breast tissue develop improves our knowledge of breast cancer. TAZ represents a potential new target for drug therapies to treat aggressive types of breast cancer.In cancer, normal cells can become unpredictable or aggressive and thus difficult to treat with anti-cancer drugs. This is especially true in breast cancer. By identifying the genes responsible for this change in cells from breast tissue, researchers hope to identify a way to stop or reverse it.

Hypertension treatment for minority patients unaffected by physician bias

Date: Mar-10-2014
Doctors' unconscious biases favor whites but do not affect high blood pressure treatment for their minority patients, according to a University of Colorado Boulder study, even though a previous study by the same research group found that doctors' biases are reflected in lower ratings by African-American patients.The new research, led by Irene Blair, an associate professor in CU-Boulder's Department of Psychology and Neuroscience, is published in the Journal of General Internal Medicine.

Computers enable researchers to "see" neurons to better understand brain function

Date: Mar-10-2014
A study conducted by local high school students and faculty from the Department of Computer and Information Science in the School of Science at Indiana University-Purdue University Indianapolis reveals new information about the motor circuits of the brain that may one day help those developing therapies to treat conditions such as stroke, schizophrenia, spinal cord injury or Alzheimer's disease."MRI and CAT scans of the human brain can tell us many things about the structure of this most complicated of organs, formed of trillions of neurons and the synapses via which they communicate.

Epigenetics and oral health

Date: Mar-10-2014
A visit to the dentist could one day require a detailed look at how genes in a patient's body are being switched on or off, as well as examining their pearly whites, according to researchers at the University of Adelaide.In a new paper published in the Australian Dental Journal, researchers from the University of Adelaide's School of Dentistry have written about the current and future use of the field of epigenetics as it relates to oral health.