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Altered glycosylation patterns protect tumors from NK cells
Date: Feb-27-2014Compared to other diseased cells, malignant tumor cells often exhibit modified surface glycosylation patterns, potentially altering recognition by host immune cells. Natural killer (NK) cells are sentinels of cancer immunosurveillanc system and express multiple receptors that allow for discrimination between healthy and malignant cells.
Children's health can be affected by anti-vaccine conspiracy theories
Date: Feb-27-2014A belief in anti-vaccine conspiracy theories may have significant and detrimental consequences for children's health, new research from the University has shown.Researchers Daniel Jolley and Dr Karen Douglas, of the School of Psychology, surveyed 89 parents about their views on anti-vaccine conspiracy theories and then asked them to indicate their intention to have a fictional child vaccinated. It was found that stronger belief in anti-vaccine conspiracy theories was associated with lower intention to vaccinate.
Clinical trial assesses anti-FGF23 for treating X-linked hypophosphatemia
Date: Feb-27-2014X-linked hypophosphatemia (XLH) is a heritable form of rickets that results from mutations in the gene encoding the phosphate regulating endopeptidase (PHEX). Unlike diet-associated forms of rickets, XLH cannot be ameliorated by vitamin D ingestion. XLH patients have increased serum levels of FGF23, which decreases both inorganic phosphate (Pi) and the activated form of vitamin D.
MERS virus widespread in Saudi Arabian camels
Date: Feb-27-2014The coronavirus responsible for Middle East Respiratory Syndrome (MERS) is prevalent in camels throughout Saudi Arabia and has been around for at least 20 years, according to a study published in mBio®, the online open-access journal of the American Society for Microbiology."Our study shows the MERS coronavirus (MERS-CoV) is widespread," says senior study author W. Ian Lipkin of Columbia University, New York. "Adult camels were more likely to have antibodies to the virus while juveniles were more likely to have active virus.
Clinical trial assesses anti-FGF23 for treating X-linked hypophosphatemia
Date: Feb-27-2014X-linked hypophosphatemia (XLH) is a heritable form of rickets that results from mutations in the gene encoding the phosphate regulating endopeptidase (PHEX). Unlike diet-associated forms of rickets, XLH cannot be ameliorated by vitamin D ingestion. XLH patients have increased serum levels of FGF23, which decreases both inorganic phosphate (Pi) and the activated form of vitamin D.
African Americans encounter more alcohol problems despite lower levels of consumption
Date: Feb-27-2014A theoretical paper with lead author Tamika Zapolski, Ph.D., assistant professor of psychology in the School of Science at Indiana University-Purdue University Indianapolis (IUPUI), examines a paradox in African American drinking. African Americans report initiation to drinking at an older age, lower rates of use and lower levels of use in nearly all age groups. Nonetheless, the group encounters higher levels of problems related to alcohol when compared to European Americans.
African Americans encounter more alcohol problems despite lower levels of consumption
Date: Feb-27-2014A theoretical paper with lead author Tamika Zapolski, Ph.D., assistant professor of psychology in the School of Science at Indiana University-Purdue University Indianapolis (IUPUI), examines a paradox in African American drinking. African Americans report initiation to drinking at an older age, lower rates of use and lower levels of use in nearly all age groups. Nonetheless, the group encounters higher levels of problems related to alcohol when compared to European Americans.
Tuberculosis and other mycobacteria destroyed by vinegar
Date: Feb-27-2014The active ingredient in vinegar, acetic acid, can effectively kill mycobacteria, even highly drug-resistant Mycobacterium tuberculosis, an international team of researchers from Venezuela, France, and the US reports in mBio®, the online open-access journal of the American Society for Microbiology.Acetic acid might be used as an inexpensive and non-toxic disinfectant against drug-resistant tuberculosis (TB) bacteria as well as other stubborn, disinfectant-resistant mycobacteria.Work with drug-resistant tuberculosis bacteria carries serious biohazard risks.
Breakthrough in Alzheimer's research
Date: Feb-27-2014A team of international scientists, including a researcher from Simon Fraser University, has isolated a gene thought to play a causal role in the development of Alzheimer's disease. The Proceedings of the National Academy of Sciences recently published the team's study.The newly identified gene affects accumulation of amyloid-beta, a protein believed to be one of the main causes of the damage that underpins this brain disease in humans.The gene encodes a protein that is important for intracellular transportation.
MERS virus widespread in Saudi Arabian camels
Date: Feb-27-2014The coronavirus responsible for Middle East Respiratory Syndrome (MERS) is prevalent in camels throughout Saudi Arabia and has been around for at least 20 years, according to a study published in mBio®, the online open-access journal of the American Society for Microbiology."Our study shows the MERS coronavirus (MERS-CoV) is widespread," says senior study author W. Ian Lipkin of Columbia University, New York. "Adult camels were more likely to have antibodies to the virus while juveniles were more likely to have active virus.
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