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Refining genomic predictors of resistance offers potential to breed cattle more resistant to TB

Date: Feb-14-2014
Scientists have identified genetic traits in cattle that might allow farmers to breed livestock with increased resistance to bovine tuberculosis (TB).The study, which compared the genetic code of TB-infected animals with that of disease-free cattle, could help to impact on a disease that leads to major economic losses worldwide.The research, led by the University of Edinburgh's Roslin Institute, has identified a number of genetic signatures associated with TB resistance in the cows that remained unaffected.

Capillaries will measure diffusion and help in more efficient medical treatment

Date: Feb-14-2014
How strongly do two dissolved analytes react with each other? Such information is of paramount importance not only in chemistry and molecular biology, but also in medicine or pharmacy, where it is used, i.e., to determine optimal drug doses. A method developed in the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw will allow for determining diffusion coefficients of analytes in fluids and equilibrium constants of reactions - quickly, at low cost, and most importantly: universally.

Capillaries will measure diffusion and help in more efficient medical treatment

Date: Feb-14-2014
How strongly do two dissolved analytes react with each other? Such information is of paramount importance not only in chemistry and molecular biology, but also in medicine or pharmacy, where it is used, i.e., to determine optimal drug doses. A method developed in the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw will allow for determining diffusion coefficients of analytes in fluids and equilibrium constants of reactions - quickly, at low cost, and most importantly: universally.

Gene identified that offers a new target for psoriasis treatment

Date: Feb-14-2014
Researchers at King's College London have identified a new gene (PIM1), which could be an effective target for innovative treatments and therapies for the human autoimmune disease, psoriasis.Psoriasis affects around 2 per cent of people in the UK and causes dry, red lesions on the skin which can become sore or itchy and can have significant impact on the sufferer's quality of life.It is thought that psoriasis is caused by a problem with the body's immune system in which new skin cells are created too rapidly, causing a build up of flaky patches on the skin's surface.

New discovery could uncover 'missing link' in genetics

Date: Feb-14-2014
Researchers believe that susceptibility to common diseases stems from a combination of common genetic variants and a variety of rare genetic mutations. But this only accounts for a small proportion of potential heritable risk factors for disease. Now, new research has discovered that some genetic variants could indicate the presence of rare genetic mutations that have yet to be discovered, which may contribute to the risk of common diseases.This is according to a study recently published in the journal PLOS Genetics.

Link between excess weight and brain changes that may relate to memory, emotions, and appetite

Date: Feb-14-2014
Being overweight appears related to reduced levels of a molecule that reflects brain cell health in the hippocampus, a part of the brain involved in memory, learning, and emotions, and likely also involved in appetite control, according to a study performed by researchers at SUNY Downstate Medical Center and other institutions. The results of the study were published in Neuroimage: Clinical.Jeremy D.

Childhood clues to later risk of STDs

Date: Feb-14-2014
Here's yet another reason to focus on kids' early years. Children who grow up in well-managed households, enjoy school, and have friends who stay out of trouble report fewer sexually transmitted diseases in young adulthood, according to a new analysis.The findings, from University of Washington longitudinal surveys of nearly 2,000 participants, suggest that efforts to curb the spread of sexually transmitted diseases should begin years before most people start having sex.

Nanoparticles treat muscular dystrophy in mouse model

Date: Feb-14-2014
Researchers at Washington University School of Medicine in St. Louis have demonstrated a new approach to treating muscular dystrophy. Mice with a form of this muscle-weakening disease showed improved strength and heart function when treated with nanoparticles loaded with rapamycin, an immunosuppressive drug recently found to improve recycling of cellular waste.The study appears online in The FASEB Journal.The investigators, including first author Kristin P. Bibee, MD, PhD, looked at a mouse model of Duchenne muscular dystrophy, the most severe inherited form of the disease.

Nanoparticles treat muscular dystrophy in mouse model

Date: Feb-14-2014
Researchers at Washington University School of Medicine in St. Louis have demonstrated a new approach to treating muscular dystrophy. Mice with a form of this muscle-weakening disease showed improved strength and heart function when treated with nanoparticles loaded with rapamycin, an immunosuppressive drug recently found to improve recycling of cellular waste.The study appears online in The FASEB Journal.The investigators, including first author Kristin P. Bibee, MD, PhD, looked at a mouse model of Duchenne muscular dystrophy, the most severe inherited form of the disease.

Nanoparticles treat muscular dystrophy in mouse model

Date: Feb-14-2014
Researchers at Washington University School of Medicine in St. Louis have demonstrated a new approach to treating muscular dystrophy. Mice with a form of this muscle-weakening disease showed improved strength and heart function when treated with nanoparticles loaded with rapamycin, an immunosuppressive drug recently found to improve recycling of cellular waste.The study appears online in The FASEB Journal.The investigators, including first author Kristin P. Bibee, MD, PhD, looked at a mouse model of Duchenne muscular dystrophy, the most severe inherited form of the disease.