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Side effects could be minimized by electronically controlled drugs
Date: Feb-07-2014Potential side effects of many of today's therapeutic drugs can be downright frightening - just listen carefully to a drug commercial on TV. These effects often occur when a drug is active throughout the body, not just where and when it is needed. But scientists are reporting progress on a new tailored approach to deliver medicine in a much more targeted way. The study on these new electronically controlled drugs appears in the journal ACS Nano.
The proportion of different receptor groups in the cell membrane determines cell repulsion
Date: Feb-07-2014When cells migrate in the body, for instance, during development, or when neurons establish new connections, cells need to know where they are going. A 'wrong turn' will generally cause disease or developmental disorders. The cells take direction cues from other cells with which they interact, and which they then repel after a short period of contact. Among those direction cues are ephrin ligands, recognized by Eph receptors on the cell.
New strategy for cholesterol treatment
Date: Feb-07-2014A basic research project from Aarhus University now sheds new light on the pharmaceutical industry's new hope in the field of cholesterol treatment; the results show that there is apparently another and just as effective way of reducing bad cholesterolCardiovascular diseases are the number one cause of death globally due to e.g. arteriosclerosis. The cause is increased cholesterol. There is therefore a considerable need for an effective method of treatment against increased cholesterol. Now, Danish researchers have made a discovery that may change the picture of how it must be treated.
New strategy for cholesterol treatment
Date: Feb-07-2014A basic research project from Aarhus University now sheds new light on the pharmaceutical industry's new hope in the field of cholesterol treatment; the results show that there is apparently another and just as effective way of reducing bad cholesterolCardiovascular diseases are the number one cause of death globally due to e.g. arteriosclerosis. The cause is increased cholesterol. There is therefore a considerable need for an effective method of treatment against increased cholesterol. Now, Danish researchers have made a discovery that may change the picture of how it must be treated.
Public divided on genetic testing to predict cancer risk
Date: Feb-07-2014A national poll from the University of Utah's Huntsman Cancer Institute shows 34 percent of respondents would not seek genetic testing to predict their likelihood of developing a hereditary cancer - even if the cost of the testing was not an issue.Concerns about employment and insurability were cited as the primary reason, even though current laws prohibit such discrimination.
Researchers discover longevity mutation in flies all over the globe
Date: Feb-07-2014To date, evidence that mutations in a gene called Indy could increase life span in flies and mimic calorie restriction in mammals has come only from experiments in the lab. A new study finds that the same benefit is present in naturally Indy-mutated flies descended from flies collected in the wild all over the world and going back decades. For years, researchers have been investigating how mutations of a gene called Indy (for "I'm Not Dead Yet") affect metabolism, life span, and reproductive fitness in both mammals and fruit flies.
Lead exposure implicated in criminal behavior
Date: Feb-07-2014When crime rates drop, politicians like to give themselves pats on the back for being "tough on crime." But a new theory explaining why violence has declined across the country since the 1990s is gaining credence, and it has nothing to do with the criminal justice system. An article in Chemical & Engineering News details the mounting data that suggests taking lead out of gas and paint has played a critical role.Lauren K. Wolf, associate editor at C&EN, explains that violent crimes had reached an all-time high in the U.S. in the early '90s.
Postnatal appointments after childbirth a window of opportunity for preventive care
Date: Feb-07-2014Medical associations widely recommend that women visit their obstetricians and primary care doctors shortly after giving birth, but slightly fewer than half make or keep those postpartum appointments, according to a study by Johns Hopkins researchers.The researchers found that women with pregnancy complications were more likely to see a doctor post-delivery, but overall, visit rates were low.
Circadian clock mechanisms suggest that time is of the essence
Date: Feb-07-2014New findings in mice suggest that merely changing meal times could have a significant effect on the levels of triglycerides in the liver. The results of this Weizmann Institute of Science study, recently published in Cell Metabolism, not only have important implications for the potential treatment of metabolic diseases, they may also have broader implications for most research areas in the life sciences.Many biological processes follow a set timetable, with levels of activity rising and dipping at certain times of the day.
Postnatal appointments after childbirth a window of opportunity for preventive care
Date: Feb-07-2014Medical associations widely recommend that women visit their obstetricians and primary care doctors shortly after giving birth, but slightly fewer than half make or keep those postpartum appointments, according to a study by Johns Hopkins researchers.The researchers found that women with pregnancy complications were more likely to see a doctor post-delivery, but overall, visit rates were low.
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