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Fewer years of life lost to cancer
Date: Jan-19-2014Since the enactment of the National Cancer Act in 1971, the U.S. has spent hundreds of billions of dollars in cancer research and treatment. And yet, the cancer mortality rate - the historic benchmark of progress - has only declined modestly while the mortality rates of other leading causes of death have declined substantially. This difference has led many to question whether we've made progress in the 'War on Cancer'. The answer is definitively yes according to Norris Cotton Cancer Center research published in the Journal of Clinical Oncology.
Enzyme identified that plays crucial role in resistance to flu
Date: Jan-19-2014McGill researchers, led by Dr. Maya Saleh of the Department of Medicine, have identified an enzyme, cIAP2 that helps the lungs protect themselves from the flu by giving them the ability to resist tissue damage. "It's a discovery that offers exciting new avenues for controlling influenza, since until now attempts to target the virus itself have proven challenging, especially in the face of emerging new strains of the virus," says Saleh, who is also a researcher at the Research Institute of the McGill University Health Centre (RI-MUHC).
Enzyme identified that plays crucial role in resistance to flu
Date: Jan-19-2014McGill researchers, led by Dr. Maya Saleh of the Department of Medicine, have identified an enzyme, cIAP2 that helps the lungs protect themselves from the flu by giving them the ability to resist tissue damage. "It's a discovery that offers exciting new avenues for controlling influenza, since until now attempts to target the virus itself have proven challenging, especially in the face of emerging new strains of the virus," says Saleh, who is also a researcher at the Research Institute of the McGill University Health Centre (RI-MUHC).
Ashamed after a doctor's visit? It could be due to self-contempt
Date: Jan-18-2014Chances are when you visit your doctor, whether it is for an illness or to discuss a new diet plan, you are probably going there with the aim of feeling better. But research suggests that around 50% of us feel guilty or ashamed when we leave a doctor's appointment.A 2009 study conducted by Christine Harris, professor of psychology at the University of California, San Diego, first identified that over half of patients experience guilt or shame when they leave a doctor's office.
Carbon nanotubes promise improved flame-resistant coating
Date: Jan-18-2014Using an approach akin to assembling a club sandwich at the nanoscale, National Institute of Standards and Technology (NIST) researchers have succeeded in crafting a uniform, multi-walled carbon-nanotube-based coating that greatly reduces the flammability of foam commonly used in upholstered furniture and other soft furnishings.The flammability of the nanotube-coated polyurethane foam was reduced 35 percent compared with untreated foam. As important, the coating prevented melting and pooling of the foam, which generates additional flames that are a major contributor to the spread of fires.
Clarifying mode of action of a targeted treatment for leukemia
Date: Jan-18-2014The mechanism of senescence - or premature cell ageing - can have an anticancer effect. This new work, conducted by Hugues de Thé and his team (Paris Diderot University/ Inserm/ CNRS/ AP-HP), was published in Nature Medicine. It reveals that targeted treatments for acute promyelocytic leukaemia, a rare form of blood cancer, cause a cascade of molecular events leading to cellular senescence and recovery. This action model could be activated in other types of cancers. The PML/RARA* protein causes the proliferation of cancer cells in patients affected by acute promyelocytic leukaemia.
Potential treatment to improve heart health in hemodialysis patients
Date: Jan-18-2014Researchers at Wayne State University have discovered a potential way to improve the lipid profiles in patients undergoing hemodialysis that may prevent cardiovascular disease common in these patients. Patients undergoing hemodialysis for kidney failure are at a greater risk for atherosclerosis, a common disease in which plaque builds up inside the arteries. Atherosclerosis can lead to serious problems including heart attack, stroke or even death.The team of researchers discovered that a unique combination of vitamin E isomers known as tocotrienols improved the patients' lipid profiles.
Gender equity and well-being promoted by parental leave policies
Date: Jan-18-2014Government policies that allow both parents to take time off after a child is born provide positive benefits for the physical and mental health of women, according to a literature review that looked at the influence of public policies on women's overall health.The findings were published in the journal Epidemiologic Reviews.Parental leave policies tended to reduce the physical and mental stress levels in women who, historically, held the majority of the burden childcare and household responsibilities, said Dr.
New candidate antimalarials for fighting drug-resistant malaria
Date: Jan-18-2014Malaria is one of the most deadly infectious diseases in the world today, claiming the lives of over half a million people every year, and the recent emergence of parasites resistant to current treatments threatens to undermine efforts to control the disease. Researchers are now onto a new strategy to defeat drug-resistant strains of the parasite. Their report appears in the journal ACS Chemical Biology.
Discovery could lead to a test to predict later development of type 2 diabetes
Date: Jan-18-2014A Montreal research team led by Jennifer Estall at the IRCM discovered that a protein found in muscle tissue may contribute to the development of type 2 diabetes later in life. The study's results, published in the printed edition of the scientific journal American Journal of Physiology - Endocrinology and Metabolism, indicate that the protein could be a promising early predictor of increased diabetes risk. "My team and I studied PGC-1α, a protein responsible for regulating the production of energy in cells," explains Dr.
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