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Novel approach to predict outcomes in heart failure patients

Date: Dec-18-2013
Researchers at the George Washington University School of Medicine and Health Sciences (SMHS) and Johns Hopkins University School of Medicine have identified a new method to determine whether a patient's heart will fail, which in the future may help physicians better treat patients and tailor therapeutic interventions. Their novel approach may help predict which patients with heart failure will do well and which patients will not. Heart failure affects five million individuals in the U.S.

Metastatic breast cancer patients with elevated circulating tumor cells do not benefit from changing chemo

Date: Dec-18-2013
For women with metastatic breast cancer who had elevated amounts of circulating tumor cells (CTCs) in their blood after a first line of chemotherapy, switching immediately to a different chemotherapy did not improve overall survival or time to progression, according to the results of a phase III clinical trial presented at the 2013 San Antonio Breast Cancer Symposium."We concluded that CTCs are not a good marker in helping to decide when to switch between chemotherapies," said Jeffrey B. Smerage, M.D., Ph.D.

Metastatic breast cancer patients with elevated circulating tumor cells do not benefit from changing chemo

Date: Dec-18-2013
For women with metastatic breast cancer who had elevated amounts of circulating tumor cells (CTCs) in their blood after a first line of chemotherapy, switching immediately to a different chemotherapy did not improve overall survival or time to progression, according to the results of a phase III clinical trial presented at the 2013 San Antonio Breast Cancer Symposium."We concluded that CTCs are not a good marker in helping to decide when to switch between chemotherapies," said Jeffrey B. Smerage, M.D., Ph.D.

Public, patients, and doctors confuse palliative care with end of life care

Date: Dec-18-2013
A new review says palliative care's association with end of life has created an "identity problem" that means the majority of patients facing a serious illness do not benefit from treatment of the physical and psychological symptoms that occur throughout their disease. The editorial is co-authored by palliative care experts at Harvard Medical School, Massachusetts General Hospital, the American Cancer Society, and Johns Hopkins University, and appears in the New England Journal of Medicine.

Progression of advanced breast cancer not delayed by new combination therapy

Date: Dec-18-2013
Adding the antibody therapy ramucirumab to the chemotherapy drug docetaxel did not delay disease progression for patients with HER2-negative, advanced breast cancer, according to results of a placebo-controlled, randomized, phase III clinical trial presented at the 2013 San Antonio Breast Cancer Symposium."Patients with metastatic or recurrent breast cancer, as well as those with locally advanced disease that cannot be surgically removed, have no curative options," said John R. Mackey, M.D., professor of oncology at the University of Alberta in Edmonton.

PET scans and saxitoxin allow researchers to 'see' pain

Date: Dec-18-2013
Scientists have long struggled to understand the science behind pain. At present, most diagnoses rely on subjective methods, such as self-reporting from patients and physical examinations. But there is currently no existing method of measuring pain intensity objectively.Pain is always a subjective experience, as no one really knows how much pain another person is feeling. What one person describes as agonizing, another may call excruciating.

Novel approach to predict outcomes in heart failure patients

Date: Dec-18-2013
Researchers at the George Washington University School of Medicine and Health Sciences (SMHS) and Johns Hopkins University School of Medicine have identified a new method to determine whether a patient's heart will fail, which in the future may help physicians better treat patients and tailor therapeutic interventions. Their novel approach may help predict which patients with heart failure will do well and which patients will not. Heart failure affects five million individuals in the U.S.

Practice, not innate skill, makes for good mathematicians

Date: Dec-18-2013
New research at the Norwegian University of Science and Technology (NTNU) in Trondheim could have an effect on how math is taught.If you want to be really good at all types of math, you need to practice them all. You can't trust your innate natural talent to do most of the job for you.This might seem obvious to some, but it goes against the traditional view that if you are good at math, it is a skill that you are simply born with.Professor Hermundur Sigmundsson at Department of Psychology is one of three researchers involved in the project.

Increased risk of death in patients receiving etomidate for anesthesia

Date: Dec-18-2013
Patients receiving the widely used anesthesia drug etomidate for surgery may be at increased risk or mortality and cardiovascular events, according to a study in the December issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).The study adds to safety concerns over etomidate's use as an anesthetic and sedative drug.

Increased risk of death in patients receiving etomidate for anesthesia

Date: Dec-18-2013
Patients receiving the widely used anesthesia drug etomidate for surgery may be at increased risk or mortality and cardiovascular events, according to a study in the December issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).The study adds to safety concerns over etomidate's use as an anesthetic and sedative drug.