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Chemists crack the code of cataract creation

Date: Dec-09-2013
Groundbreaking new findings by UC Irvine and German chemists about how cataracts form could be used to help prevent the world's leading cause of blindness, which currently affects nearly 20 million people worldwide. (PDF)"That's the dream, and this is a big step," said Rachel Martin, UC Irvine associate professor of chemistry and co-author of a paper featured on the December cover of the journal Structure.

Identifying patients admitted to hospital who are at risk of death within a year

Date: Dec-09-2013
A University of Colorado Cancer Center study recently published in the Journal of Hospital Medicine validates a prognostic tool that determines risk of death within a year of hospital admission, helping doctors match treatments to patients' values and goals of care."There are many prognostic indices, but until now none meant to be used immediately upon hospital admission," says Stacy Fischer, MD, CU Cancer Center investigator and assistant professor of internal medicine at the University of Colorado School of Medicine.

Identifying patients admitted to hospital who are at risk of death within a year

Date: Dec-09-2013
A University of Colorado Cancer Center study recently published in the Journal of Hospital Medicine validates a prognostic tool that determines risk of death within a year of hospital admission, helping doctors match treatments to patients' values and goals of care."There are many prognostic indices, but until now none meant to be used immediately upon hospital admission," says Stacy Fischer, MD, CU Cancer Center investigator and assistant professor of internal medicine at the University of Colorado School of Medicine.

Menstrual cramping may be alleviated by vaginally administered sildenafil citrate

Date: Dec-09-2013
Women with moderate to severe menstrual cramps may find relief in a class of erectile dysfunction drugs, according to a team of researchers led by Penn State College of Medicines Richard Legro.Primary dysmenorrhea, also called PD, is the most common cause of pelvic pain in women. The current treatment is non-steroidal anti-inflammatory drugs, such as ibuprofen. However, ibuprofen does not work well for all women, and can be associated with ulcers and kidney damage when used chronically as it often is for PD.

Menstrual cramping may be alleviated by vaginally administered sildenafil citrate

Date: Dec-09-2013
Women with moderate to severe menstrual cramps may find relief in a class of erectile dysfunction drugs, according to a team of researchers led by Penn State College of Medicines Richard Legro.Primary dysmenorrhea, also called PD, is the most common cause of pelvic pain in women. The current treatment is non-steroidal anti-inflammatory drugs, such as ibuprofen. However, ibuprofen does not work well for all women, and can be associated with ulcers and kidney damage when used chronically as it often is for PD.

Critical-Care Pain Observation Tool validated for pain assessment in patients following cardiac surgery

Date: Dec-09-2013
How do you measure the pain of a patient who can't communicate? A Rhode Island Hospital researcher studied an observational pain scale in cardiac surgery patients, and found that the Critical-Care Pain Observation Tool (CPOT) provided an accurate measure of a patient's pain level. The study by Sandra Linde, RN, is the first study conducted in Rhode Island Hospital's Clinical Nurse Scholar program, in which direct care nurses are mentored to serve as principal investigators. The paper is published in the American Journal of Critical Care.

Critical-Care Pain Observation Tool validated for pain assessment in patients following cardiac surgery

Date: Dec-09-2013
How do you measure the pain of a patient who can't communicate? A Rhode Island Hospital researcher studied an observational pain scale in cardiac surgery patients, and found that the Critical-Care Pain Observation Tool (CPOT) provided an accurate measure of a patient's pain level. The study by Sandra Linde, RN, is the first study conducted in Rhode Island Hospital's Clinical Nurse Scholar program, in which direct care nurses are mentored to serve as principal investigators. The paper is published in the American Journal of Critical Care.

Insulin sensitizers reduce risk of cancer

Date: Dec-09-2013
A Cleveland Clinic-led study shows that a specific type of diabetes drug can decrease the risk of cancer in female patients with type 2 diabetes by up to 32 percent.People with type 2 diabetes have a higher rate of cancer development and recurrence compared to the general population. This study - published online by the journal Diabetes, Obesity and Metabolism - shows that widely prescribed anti-diabetes drugs can be linked to either an increased or decreased risk of cancer, depending on the type of medication prescribed.A team of researchers led by Sangeeta Kashyap, M.D.

Insulin sensitizers reduce risk of cancer

Date: Dec-09-2013
A Cleveland Clinic-led study shows that a specific type of diabetes drug can decrease the risk of cancer in female patients with type 2 diabetes by up to 32 percent.People with type 2 diabetes have a higher rate of cancer development and recurrence compared to the general population. This study - published online by the journal Diabetes, Obesity and Metabolism - shows that widely prescribed anti-diabetes drugs can be linked to either an increased or decreased risk of cancer, depending on the type of medication prescribed.A team of researchers led by Sangeeta Kashyap, M.D.

Ruggedly built, tree-climbing human ancestor improves understanding of how humans evolved

Date: Dec-09-2013
A human ancestor characterized by "robust" jaw and skull bones was a muscular creature with a gorilla-like upper body and more adaptive to its environment than previously thought, scientists have discovered.Researchers found a partial skeleton -- including arm, hand, leg and foot fragments -- dated to 1.34 million years old and belonging to Paranthropus boisei at the Olduvai Gorge World Heritage fossil site in Tanzania. The find, published in the latest edition of the scientific journal PLOS ONE, represents one of the most recent occurrences of P.