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Risk of HIV treatment failure present even in those with low viral load

Date: Nov-27-2013
People with human immunodeficiency virus (HIV) run a higher risk of virologic failure than previously thought, even when their number of RNA copies of the retrovirus per millilitre of blood is slightly above the detection threshold, according to a study by Claudie Laprise at the University of Montreal's Department of Social and Preventative Medicine. Her findings were published in Clinical Infectious Diseases.

FDA approves Varithena for the treatment of patients with varicose veins

Date: Nov-27-2013
BTG plc (LSE: BTG), the specialist healthcare company, has announced that the US Food and Drug Administration (FDA) has approved Varithena™ (polidocanol injectable foam) for the treatment of patients with incompetent veins and visible varicosities of the great saphenous vein (GSV) system.1 Varithena™ (formerly known as Varisolve PEM) is a pharmaceutical-grade, low-nitrogen, polidocanol foam dispensed from a proprietary canister device.

Shortage of rheumatologists - in some U.S. regions closest doctor may be 200 miles away

Date: Nov-27-2013
A novel study published in the American College of Rheumatology (ACR) journal, Arthritis & Rheumatism, shows that smaller micropolitan areas of the U.S. - those with less than 50,000 people - have very few or no practicing adult rheumatologist. In some of these areas, individuals have to travel more than 200 miles to reach the closest rheumatologist.A 2005 ACR workforce study examining the number of adult practicing rheumatologists in the United States estimated there to be roughly 1.7 adult rheumatologists per 100,000 persons.

Obese women at higher risk of hearing loss but physical activity associated with lower risk

Date: Nov-27-2013
According to the World Health Organization, 360 million people have disabling hearing loss, a condition that is often considered to be an unavoidable side effect of aging. New research from Brigham and Women's Hospital (BWH) published online in The American Journal of Medicine, finds that a higher body mass index (BMI) and larger waist circumference are each associated with higher risk of hearing loss, while a higher level of physical activity is associated with lower risk of hearing loss in women.

A mechanism that favors rejection in transplantation of porcine cartilage in humans

Date: Nov-27-2013
Researchers at the Bellvitge Institute of Biomedical Research (IDIBELL) led by Cristina Costa from the New Therapies on Genes and Transplantation group have shown that inhibition of one of the basic components of the complement system protects chondrocytes (cartilage cells) from porcine rejection of xenotransplantation (transplantation between animals of different species).Complement systemThe complement system is a key component in the process of innate immunity.

Nanoscale 'patches' sensitize targeted cell receptors

Date: Nov-27-2013
Researchers from North Carolina State University and Duke University have developed nanoscale "patches" that can be used to sensitize targeted cell receptors, making them more responsive to signals that control cell activity. The finding holds promise for promoting healing and facilitating tissue engineering research.The research takes advantage of the fact that cells in a living organism can communicate via physical contact. Specifically, when targeted receptors on the surface of a cell are triggered, the cell receives instructions to alter its behavior in some way.

Novel new immuno-therapy for malignant brain tumors

Date: Nov-27-2013
Glioblastoma is one of the most ominous brain tumors. Despite aggressive surgery, radiation and chemotherapy the outcome of this disease is almost always fatal. A UZH research team has now achieved success with a novel form of treatment that involves encouraging the body's own immune system to recognise and eliminate cancer cells in the brain.Animal experiments show that it is relatively easy to treat cancer in the early stages. However, it is far more difficult to successfully treat advanced cancer.

Future anti-inflammatory drugs for chronic inflammation diseases may come from coumarins

Date: Nov-27-2013
New methods for the laboratory-scale synthesis of coumarin-based drugs were developed in a recent study completed at the University of Eastern Finland. In his doctoral thesis, Lic. Phil. Juri Timonen also developed new analytical methods for the fast identification of natural and non-natural coumarins. A few of the synthesised coumarins were also found to inhibit some specific reactions generally associated with inflammation.Coumarin is an aromatic compound, naturally occurring in many plants. In foodstuffs coumarins are found especially in cinnamon and tonka beans.

Autistic children's ability to perform everyday tasks improved by occupational therapy

Date: Nov-27-2013
In one of the first randomized control trials studying an intervention for sensory problems in children with autism, researchers found that occupational therapy using the principles of Sensory Integration (OT-SI) provided better outcomes on parent-identified goals than standard care, according to results published in the Journal of Autism and Developmental Disorders. OT-SI therapy for autism is based on the premise that difficulty interpreting sensory information affects the ability to participate fully in everyday activities including eating, dressing, learning and play activities.

1 in 10 high school students affected by dating violence

Date: Nov-27-2013
One in 10 high school youth in the U.S. reports having been hit or physically hurt by a dating partner in the past year, according to a new study led by a Boston University School of Public Health researcher.In a study published in the Journal of School Violence, Emily Rothman and Ziming Xuan, faculty at Boston University, analyzed data from 100,901 students who participated in the national Youth Risk Behavior Surveillance System survey (YRBSS) for the years 1999-2011. They found that 9.3 percent of U.S.